| Man City | 6-3 | RB Leipzig |
| Brujas | 1-1 | PSG |
| RB Leipzig | 28-09 21:00 | Brujas |
| PSG | 28-09 21:00 | Man City |
| Brujas | 19-10 18:45 | Man City |
| PSG | 19-10 21:00 | RB Leipzig |
| Man City | 03-11 21:00 | Brujas |
| RB Leipzig | 03-11 21:00 | PSG |
| Man City | 24-11 21:00 | PSG |
| Brujas | 24-11 21:00 | RB Leipzig |
| PSG | 07-12 18:45 | Brujas |
| RB Leipzig | 07-12 18:45 | Man City |
| Liverpool | 3-2 | Milan |
| Atlético | 0-0 | Porto |
| Porto | 28-09 21:00 | Liverpool |
| Milan | 28-09 21:00 | Atlético |
| Porto | 19-10 21:00 | Milan |
| Atlético | 19-10 21:00 | Liverpool |
| Milan | 03-11 18:45 | Porto |
| Liverpool | 03-11 21:00 | Atlético |
| Liverpool | 24-11 21:00 | Porto |
| Atlético | 24-11 21:00 | Milan |
| Porto | 07-12 21:00 | Atlético |
| Milan | 07-12 21:00 | Liverpool |
| Besiktas | 1-2 | Borussia Dortmund |
| Sporting CP | 1-5 | Ajax |
| Ajax | 28-09 18:45 | Besiktas |
| Borussia Dortmund | 28-09 21:00 | Sporting CP |
| Besiktas | 19-10 18:45 | Sporting CP |
| Ajax | 19-10 21:00 | Borussia Dortmund |
| Sporting CP | 03-11 21:00 | Besiktas |
| Borussia Dortmund | 03-11 21:00 | Ajax |
| Besiktas | 24-11 18:45 | Ajax |
| Sporting CP | 24-11 21:00 | Borussia Dortmund |
| Borussia Dortmund | 07-12 21:00 | Besiktas |
| Ajax | 07-12 21:00 | Sporting CP |
| Sheriff | 2-0 | Shakhtar |
| Inter Milán | 0-1 | Real Madrid |
| Shakhtar | 28-09 18:45 | Inter Milán |
| Real Madrid | 28-09 21:00 | Sheriff |
| Inter Milán | 19-10 21:00 | Sheriff |
| Shakhtar | 19-10 21:00 | Real Madrid |
| Real Madrid | 03-11 18:45 | Shakhtar |
| Sheriff | 03-11 21:00 | Inter Milán |
| Inter Milán | 24-11 18:45 | Shakhtar |
| Sheriff | 24-11 21:00 | Real Madrid |
| Real Madrid | 07-12 21:00 | Inter Milán |
| Shakhtar | 07-12 21:00 | Sheriff |
| FC Barcelona | 0-3 | Bayern Munich |
| Dinamo Kiev | 0-0 | Benfica |
| Benfica | 29-09 21:00 | FC Barcelona |
| Bayern Munich | 29-09 21:00 | Dinamo Kiev |
| FC Barcelona | 20-10 18:45 | Dinamo Kiev |
| Benfica | 20-10 21:00 | Bayern Munich |
| Bayern Munich | 02-11 21:00 | Benfica |
| Dinamo Kiev | 02-11 21:00 | FC Barcelona |
| Dinamo Kiev | 23-11 18:45 | Bayern Munich |
| FC Barcelona | 23-11 21:00 | Benfica |
| Benfica | 08-12 21:00 | Dinamo Kiev |
| Bayern Munich | 08-12 21:00 | FC Barcelona |
| Young Boys | 2-1 | Man Utd. |
| Villarreal | 2-2 | Atalanta |
| Atalanta | 29-09 18:45 | Young Boys |
| Man Utd. | 29-09 21:00 | Villarreal |
| Man Utd. | 20-10 21:00 | Atalanta |
| Young Boys | 20-10 21:00 | Villarreal |
| Villarreal | 02-11 21:00 | Young Boys |
| Atalanta | 02-11 21:00 | Man Utd. |
| Villarreal | 23-11 18:45 | Man Utd. |
| Young Boys | 23-11 21:00 | Atalanta |
| Man Utd. | 08-12 21:00 | Young Boys |
| Atalanta | 08-12 21:00 | Villarreal |
| Sevilla | 1-1 | Salzburgo |
| Lille | 0-0 | Wolfsburgo |
| Wolfsburgo | 29-09 21:00 | Sevilla |
| Salzburgo | 29-09 21:00 | Lille |
| Salzburgo | 20-10 18:45 | Wolfsburgo |
| Lille | 20-10 21:00 | Sevilla |
| Wolfsburgo | 02-11 18:45 | Salzburgo |
| Sevilla | 02-11 21:00 | Lille |
| Sevilla | 23-11 21:00 | Wolfsburgo |
| Lille | 23-11 21:00 | Salzburgo |
| Wolfsburgo | 08-12 21:00 | Lille |
| Salzburgo | 08-12 21:00 | Sevilla |
| Chelsea | 1-0 | Zenit |
| Malmö | 0-3 | Juventus |
| Zenit | 29-09 18:45 | Malmö |
| Juventus | 29-09 21:00 | Chelsea |
| Chelsea | 20-10 21:00 | Malmö |
| Zenit | 20-10 21:00 | Juventus |
| Malmö | 02-11 18:45 | Chelsea |
| Juventus | 02-11 21:00 | Zenit |
| Chelsea | 23-11 21:00 | Juventus |
| Malmö | 23-11 21:00 | Zenit |
| Juventus | 08-12 18:45 | Malmö |
| Zenit | 08-12 18:45 | Chelsea |
Octavos
Cuartos
Semifinales
Final
