Midfielder Nico Gonzalez and goalkeeper Iñaki Peña trained with Barcelona's B team this weekend and could be involved in Saturday's game away against Nastic de Tarragona.
Nico and Peña have both been involved with the first team this season but with the international break have dropped down to the reserve team.
Coach Sergi Barjuan will have them available for what is Barça B's second game of the season in the restructured third tier of Spanish football, known as the Primera RFEF.
Barça kicked off the campaign at the Estadi Johan Cruyff last weekend against Algeciras, drawing 1-1.
Nico came off the bench, meanwhile, on Sunday as Barça beat Getafe in LaLiga, while Peña has been an unused substitute since featuring in preseason for the first team.